Sunday, November 4, 2012

What Happens When There's Not Enough


Zinc Deficiency: Serious Business

While it is unlikely for a person living in the US today to become zinc deficient, about 2 billion people world wide suffer from a lack of this mineral. The impact of zinc deficiency was discovered about 49 years ago, and the world is forever improved because of it. Zinc deficiency can cause many negative effects on the human body including but not limited to growth retardation, hypergonadism, immune dysfunction as well as cognitive impairment. Zinc has been shown to be an intracellular signaling molecule in monocytes, dendritic cells and macrophages and it plays an important role in cell-mediated immune functions and oxidative stress. Zinc supplementation has proven an affective treatment for diarrhea in children, blindness in the elderly, various infections. It also decreased oxidative stress and decreased the generation of inflammatory cytokines. Clinical zinc supplementation was found to help in treatment of neurological disease, atherosclerosis, and several malignancies.

These represent some of the more serious effects of zinc deficiency. It is not something to be taken lightly, but it is important to note that zinc deficiency is not a common occurrence among people living in the developed world. Fortified foods ensure this, although athletes, vegetarians, and people pregnant or lactating are at an elevated risk for zinc deficiency. The above conditions result from long periods of time, or times of growth without zinc, and not a temporary imbalanced diet.



Prasad A.S. Impact of the discovery of human zinc deficiency on health. Journal of American College of Nutrition.2009;28:257–265.

1 comment:

  1. It is good to know that we are at such low risk of zinc deficiency in this country. Until reading your post, I was unaware of the potentially devastating effect of zinc deficiency. Many people I have spoken with have knocked fortified foods because they are not totally "natural," but in my opinion they are a saving grace in many circumstances. Thank you for your post!

    ReplyDelete